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Clear out junk files and repair common Windows errorsFree Scan →Scan for outdated or missing drivers - takes under a minuteDriver Scan →Repair Windows errors before they cause bigger problemsFix Now →St. Denis Medical centers on seven regular cast members playing hospital staff at an underfunded, understaffed Oregon hospital. Allison Tolman’s Alex, a supervising emergency-department nurse, is the practical point of entry; Wendi McLendon-Covey’s Joyce runs the hospital, and David Alan Grier’s Dr. Ron is a veteran physician. Here’s who plays whom, including selected Season 2 additions.
The seven regulars in St. Denis Medical
Peacock’s Season 2 cast guide names these seven actors as the series’ regular ensemble. Its April 2026 cast caption independently identifies the same actor-character pairings.
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- Wendi McLendon-Covey as Joyce: The hospital administrator and Alex’s boss. Joyce wants to turn the facility into an international medical destination.
- David Alan Grier as Dr. Ron: A veteran physician who has “done it all, seen it all.” The show’s official Season 2 description presents him as experienced and weary.
- Allison Tolman as Alex: A devoted nurse promoted to supervising nurse in the emergency department. She works alongside the hospital team.
- Josh Lawson as Dr. Bruce: A member of the regular cast.
- Kahyun Kim as Serena: A member of the regular cast.
- Mekki Leeper as Matt: A member of the regular cast.
- Kaliko Kauahi as Val: A member of the regular cast.
The official cast guide identifies Dr. Bruce, Serena, Matt, and Val by name but does not provide further character descriptions there.
Selected Season 2 additions
Peacock’s October 2025 guide identifies these Season 2 newcomers and roles:
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- Ariana Madix as Dr. Emerson
- Kristen Schaal as Ashley
- Lauren Weedman as Pam
- Frankie Quiñones as Leslie
- Jonah Beckett as Kyle
- Jeremiah Brown as Jeff
The same guide lists Lauren Lapkus and Tim Baltz among the new faces, but does not name their characters in that cast list. This is a selection of additions, not a complete guest-cast roster.
How the characters fit the hospital
St. Denis Medical is a workplace mockumentary about doctors and nurses trying to care for patients and maintain their sanity in an underfunded, understaffed Oregon hospital. The central workplace dynamic runs through Alex’s new supervisory responsibilities: Joyce is her ambitious boss, while Dr. Ron brings the perspective of a physician who has seen plenty and is tired of it all. The series’ ensemble fills out the staff around them.
Rank #2
- UPC 733961118179
Season 2 release and streaming
Season 2 premiered on NBC on November 3, 2025, with back-to-back episodes; new episodes streamed on Peacock the following day, according to NBCUniversal’s October 30, 2025 announcement and Peacock’s October 20, 2025 guide. Peacock reported on April 6, 2026 that all episodes from Seasons 1 and 2 were available to stream there; its catalog may change, so check the service for current availability. See Peacock’s streaming guide.
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Best Value
Rank #4
- Factory sealed DVD
Rank #3
- Factory sealed DVD
Product prices and availability are accurate as of the date/time indicated and are subject to change. Any price and availability information displayed on Amazon at the time of purchase will apply.
