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Joey Graziadei Explains His Gilbert Syndrome Diagnosis and Yellow-Tinged Eyes

Joey Graziadei said doctors diagnosed Gilbert syndrome after bloodwork showed high bilirubin. Here’s what the condition means and why jaundice may need medical attention.
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Joey Graziadei said his yellow-tinged eyes were linked to Gilbert syndrome, an inherited condition that can cause bilirubin to rise temporarily. In an account reported by Good Morning America on March 1, 2024, he recalled being diagnosed after bloodwork showed high bilirubin and doctors evaluated him. His story is personal, not a way to diagnose yellow eyes: jaundice has multiple possible causes, and new or unusually persistent jaundice warrants medical advice.

Why did Joey Graziadei say his eyes looked yellow?

Graziadei addressed comments about the yellow tint in the whites of his eyes in a video he shared on Instagram. As reported by Good Morning America, he said he had been sick for about a week and a half in high school when bloodwork showed high bilirubin. He recalled having a liver ultrasound and being evaluated by doctors, who, he said, found no hepatitis and diagnosed Gilbert syndrome.

He described the eye discoloration as connected to jaundice levels. He also said he considered himself healthy to his knowledge and wanted to pay closer attention to his health. These are Graziadei’s reported recollections and statements; they are not independently verified medical records or a clinical assessment of his current health.

What is Gilbert syndrome?

Gilbert syndrome is an inherited condition that affects how the liver processes bilirubin, a yellow pigment produced as red blood cells break down. When bilirubin builds up in the blood, it can cause intermittent, usually mild jaundice—yellowing of the whites of the eyes and sometimes the skin. The NHS says Gilbert syndrome does not damage the liver or affect life expectancy and usually does not cause serious health problems. Mayo Clinic’s overview also describes occasional yellowing associated with higher bilirubin.

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What can bring on a bilirubin rise?

For people with Gilbert syndrome, Mayo Clinic lists illness, fasting or a very low-calorie diet, dehydration, menstruation, strenuous exercise and stress as situations that can raise bilirubin. Graziadei mentioned stress and lack of sleep in his own account, but one person’s experience is not a complete trigger list and cannot establish a diagnosis.

Does Gilbert syndrome need treatment?

Usually, no. The NHS says Gilbert syndrome generally does not need medical treatment, and Mayo Clinic likewise says it needs no treatment. Mayo Clinic advises people with the condition to tell healthcare professionals about it because it can affect how some medicines are processed. That information is useful when discussing prescriptions or other care.

How is Gilbert syndrome diagnosed?

A clinician evaluates the person’s symptoms and test results; eye color alone cannot confirm Gilbert syndrome. The NHS says diagnosis can involve blood tests, including a liver-function check, and sometimes genetic testing. Mayo Clinic describes evaluation using blood counts, liver enzymes and bilirubin levels; genetic testing can confirm the diagnosis.

Graziadei’s account of high bilirubin, ultrasound and medical evaluation describes what he remembers from his own experience. It is not a diagnostic checklist for someone else. Anyone concerned about yellow eyes or skin should seek advice from a healthcare professional rather than infer Gilbert syndrome from appearance.

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When should jaundice be checked urgently?

Jaundice can have causes other than Gilbert syndrome. The NHS advises urgent medical advice for someone with jaundice who has not been diagnosed with Gilbert syndrome. It also advises someone who has the diagnosis to seek urgent advice if jaundice is worse than usual or does not go away within a few days. A known diagnosis should not be used to dismiss a new, more pronounced or lingering change.

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