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St. Denis Medical is a workplace mockumentary about the doctors, nurses, and staff of an underfunded Oregon hospital. The comedy follows their efforts to care for patients while navigating workplace pressures and personal lives. Its second season premiered on NBC on November 3, 2025, and streamed on Peacock the next day in the United States; that launch date has passed.
What is St. Denis Medical about?
NBC and Peacock describe the series as a mockumentary set in an underfunded, understaffed hospital in Oregon. It uses a documentary-style workplace frame to follow hospital employees as they try to do their jobs amid limited resources, demanding shifts, and personal complications. It is a comedy, not a medical procedural or a source of clinical guidance.
Showrunner Eric Ledgin summed up its premise to TheWrap: “It’s a workplace comedy in the most interesting workplace you can think of.”
Who is in the cast?
The original ensemble includes Wendi McLendon-Covey as Joyce, David Alan Grier as Dr. Ron, Allison Tolman as Alex, Josh Lawson as Dr. Bruce, Kahyun Kim as Serena, Mekki Leeper as Matt, and Kaliko Kauahi as Val.
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The central workplace dynamic
NBCUniversal’s description particularly highlights Alex, newly promoted to supervising nurse in the emergency department, alongside Joyce and veteran physician Dr. Ron. That framing offers an entry point into the ensemble without suggesting that the series gives every character identical focus.
Season-two guest additions
Peacock’s season-two guide names guest performers including Ariana Madix as Dr. Emerson, Kristen Schaal as Ashley, Lauren Weedman as Pam, Frankie Quiñones as Leslie, Lauren Lapkus, Tim Baltz, Jonah Beckett as Kyle, and Jeremiah Brown as Jeff.
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When did season two premiere?
Season two returned to NBC on Monday, November 3, 2025, with two episodes at 8/7c, according to NBCUniversal’s fall schedule. Peacock’s season-two guide gives the same launch information and says episodes streamed there the following day in the United States. These are historical launch dates, not an upcoming premiere announcement.
Peacock’s catalog listing retrieved for the season shows 18 episodes, with summaries that include a birthing-center storyline, staffing pressures, and workplace conflicts. Episode counts and catalog pages can change over time.
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Where can you watch St. Denis Medical?
For the season-two launch in the United States, the documented routes were NBC’s broadcast schedule and next-day streaming on Peacock. Peacock’s catalog availability and streaming rights may vary by date and region, so check the current listing where you live rather than assuming the series is available everywhere.
Independent reader supportYour contribution helps us test, update, and keep practical guides available for everyone.Is the medical detail meant to be realistic?
TheWrap’s 2024 set-visit report says the production consulted medical experts on jargon, procedures, and cases, and used medical technicians to help stage scenes. That is production context, not a guarantee of clinical accuracy or a reason to use the series as medical advice.
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- Featuring 6 custom sculpted weapon tokens - World’s Best Boss Coffee Mug, Poisoned Pretzel, Dundee Trophy, Bicycle Chain, Mr. A Knife, Ream of Paper, Nunchucks, Bacon Grill, and Rabid Bat
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Apple TV’s US listing identifies the series as a 2024 comedy, approximately 22 minutes per episode, rated TV-14, and originating in the United States.
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