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What Researchers Found in Beethoven’s 200-Year-Old Hair

A famous Beethoven hair lock was misattributed, while DNA from five matching locks offered separate clues about liver disease and an unexpected event in his paternal ancestry.
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A famous lock of Ludwig van Beethoven’s hair was not his. That was one surprise in a 2023 genome study—but not the only one: comparisons with living relatives also pointed to an undocumented event somewhere in Beethoven’s paternal ancestry. The findings offer clues about his health, too, without proving exactly what caused his death or deafness.

Why the Hiller lock was a surprise

The Hiller lock had long been associated with Beethoven and featured in Russell Martin’s book Beethoven’s Hair. But when researchers compared hair samples for their 2023 genome study, the Hiller lock did not match the group judged authentic. The Beethoven Center at San José State University now describes it as inauthentic. That finding corrects the attribution of this particular artifact; it does not mean every historical lock linked to Beethoven is false. The Beethoven Center’s collection account identifies a different lock, the Schindler/Moscheles lock, among the authentic samples.

How researchers chose the hair for Beethoven’s genome

The international team reported sequencing Beethoven’s genome from five hair locks that matched one another. The University of Cambridge says the locks came from the last seven years of his life. Researchers screened additional locks, and some—including the Hiller lock—did not match the authentic group. The genome therefore came from a selected set of matching samples, not from every artifact historically attributed to Beethoven. The study appeared in Current Biology on 24 April 2023; Cambridge and the Max Planck Institute for Evolutionary Anthropology also summarize the work (Cambridge; Max Planck).

What the hair suggested about Beethoven’s liver disease

Evidence of hepatitis B

The researchers reported evidence of hepatitis B virus in Beethoven’s hair. This is a finding about viral evidence in the analyzed material; on its own, it does not establish precisely when or how he was infected, or that the virus alone caused his fatal illness. The study and institutional summaries describe it as one possible contributor to severe liver disease. (Study; Max Planck summary.)

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Inherited risk and a possible combined explanation

The genome also showed genetic risk factors associated with liver disease. The researchers considered those inherited risks, hepatitis B, and alcohol consumption as factors that may have interacted and contributed to severe liver disease. That is a proposed explanation, not a definitive diagnosis of the exact cause of Beethoven’s death; the evidence does not establish one conclusive cause. (Study; Cambridge summary.)

What the relatives’ DNA revealed about Beethoven’s paternal line

When researchers compared Beethoven’s DNA with that of living relatives, the results did not fit the expected pattern for the paternal line. The team interpreted the discrepancy as evidence of an extramarital event somewhere in Beethoven’s paternal ancestry. The DNA comparison does not identify the people involved, the generation or circumstances, or when the event occurred. It therefore does not establish that the man presumed to be Beethoven’s father was not his biological father. The Max Planck summary describes the family-history finding.

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What the study did not resolve

The genome work did not identify a genetic explanation for Beethoven’s deafness. Nor do the liver-related findings provide a general explanation for all his health problems. The study adds evidence about selected aspects of his health and ancestry, but it does not settle the cause of his hearing loss or a single definitive cause of death. (Study; Cambridge summary.)

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