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Kim Kardashian’s Brain SPECT Scan: What “Holes” and “Low Activity” Mean

A report about a brain scan on The Kardashians used the words “holes” and “low activity.” Learn what SPECT imaging measures—and what it cannot establish.
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The “holes” described in a report about a The Kardashians scene are not literal gaps in Kim Kardashian’s brain. The scan shown was reportedly a SPECT scan, which maps the distribution of an injected tracer related to blood flow. A pattern described as “low activity” is an imaging finding—not, by itself, a diagnosis or an explanation of its cause.

What was reported about Kardashian’s scan?

In a December 7, 2025 report, Victor Tangermann of Futurism described a scene from The Kardashians in which physician Daniel Amen showed Kardashian a brain scan and reportedly characterized some areas as “holes” associated with “low activity.” The report says the scan was SPECT imaging. It also says Kardashian had previously received an aneurysm diagnosis after MRI scans. These are different imaging modalities, and the available reporting does not provide the actual scans or her full medical record for independent review.

The word “holes” is a visual metaphor attributed to the episode or its coverage. It should not be read as evidence that brain tissue is physically missing. Nor does a scan description alone establish a disease, a symptom’s cause, or what treatment a person needs.

What does “low activity” mean on a brain SPECT scan?

In brain perfusion SPECT, a radiotracer is injected and a scanner creates three-dimensional images showing where the tracer has distributed. Tracer distribution reflects regional blood flow, which is correlated with brain activity; it is not a direct measurement of thoughts, abilities, or the reason a region has a particular appearance. The Society of Nuclear Medicine and Molecular Imaging (SNMMI) fact sheet on molecular imaging and the brain explains the technique and its clinical context.

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Thus, “low activity” in this setting is a simplified description of a scan pattern, not a self-explanatory result. The image needs to be interpreted alongside the person’s symptoms, history, examination, and the clinical question that prompted imaging. The appearance alone does not show why blood flow differs or prove that stress caused it.

What can SPECT—and MRI—help assess?

Imaging methods measure different things. Perfusion SPECT uses tracer distribution as a functional signal related to blood flow. Conventional MRI primarily depicts anatomy and structural features. One does not automatically replace the other: clinicians choose an approach based on the question being investigated and interpret the result in context.

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SNMMI describes brain SPECT applications that include epilepsy imaging and selected dementia evaluations. Its fact sheet on molecular imaging and Alzheimer’s disease discusses imaging in that specific context. Established uses for particular clinical questions do not validate every possible interpretation or use of a scan. A finding reported from a television segment cannot be evaluated as if the full clinical work-up were available.

Does this scan show that chronic stress caused the pattern?

The report attributes an interpretation linking Kardashian’s reported scan pattern to chronic stress to Amen. That is an attributed explanation, not a causal conclusion established by the SNMMI materials cited here. Those materials explain what SPECT measures and describe selected clinical uses; they do not establish that chronic stress caused the reported appearance in Kardashian’s case.

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The report also summarizes criticism from Sarah Hellewell, a neurology senior research fellow at Curtin University, about extending SPECT interpretations beyond well-supported clinical contexts. The available sources do not establish a population prevalence for SPECT “holes,” or a validated causal link between chronic stress and this reported scan appearance. Kardashian’s actual images and full clinical record are not available here, so her individual findings cannot be independently assessed.

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How should a SPECT result be interpreted?

SNMMI says SPECT images are reviewed by a nuclear medicine physician or radiologist. A clinically meaningful interpretation also depends on the reason for the scan and relevant medical information. For an individual patient, questions about a result belong with the treating clinician and the qualified imaging professional who reviewed it.

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A 2012 prospective case series by Daniel G. Amen and coauthors reported that SPECT access modified diagnosis or treatment plans in 86 of 109 cases (78.9%). The patients were consecutive outpatients from four psychiatric clinics that routinely used SPECT in complex cases, and the authors were affiliated with Amen Clinics. The result describes that specialized case series; it does not demonstrate that broad screening is effective or establish that stress explains a particular scan pattern. The study is indexed by PubMed.

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